XIAO, DENGMING,ZHU, LI,HU, YUANDONG,WANG, SHIXIN,YU, RONG,HU, WEI,LIANG, ZHI,LIU, XIJIE,HU, QUAN
申请号：
EP11837567
公开号：
EP2635587A4
申请日:
2011.11.01
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The invention provides novel substituted 6-arylamino pyridone carboxamides represented by Formula I, or a pharmaceutically acceptable salt, solvate, poly-morph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.
