JIANG GUANG LIANG,TURKEL CATHERINE C,STERN MICHAEL,SCHAUMBURG CHRISTOPHER S,BLANDA WENDY
申请号：
IN201747026234
公开号：
IN201747026234A
申请日:
2017.07.24
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
The present invention relates to formulations for administration to a joint fat pad of a subject and to methods of treating joint pain inflammation or disease. The disclosed formulations are intended for local administration to the joint fat pad to provide sustained release of a therapeutic agent to the joint cavity and surrounding tissues. The joint may be an arthritic joint an injured joint or a surgically replaced joint. The therapeutic agent may be an analgesic agent an anti inflammatory agent or an immunosuppressive agent. A single administration of the formulation to the joint fat pad delivers a therapeutically effective amount of the therapeutic agent with reduced systemic exposure relative to a single systemic or a single intra articular administration of a therapeutic dose of an identical therapeutic agent.
