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Joint fat pad formulations, and methods of use thereof
专利权人:
Inc.;Allergan
发明人:
Jiang, Guang-Liang,Turkel, Catherine C.,Stern, Michael,Schaumburg, Christopher S.,Blanda, Wendy
申请号:
AU2016211457
公开号:
AU2016211457A1
申请日:
2016.01.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention relates to formulations for administration to a joint fat pad of a subject, and to methods of treating joint pain, inflammation or disease. The disclosed formulations are intended for local administration to the joint fat pad to provide sustained release of a therapeutic agent to the joint cavity and surrounding tissues. The joint may be an arthritic joint, an injured joint or a surgically replaced joint. The therapeutic agent may be an analgesic agent, an anti-inflammatory agent or an immunosuppressive agent. A single administration of the formulation to the joint fat pad delivers a therapeutically effective amount of the therapeutic agent with reduced systemic exposure relative to a single systemic or a single intra-articular administration of a therapeutic dose of an identical therapeutic agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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