A disposable intranasal brain-targeting drug delivery apparatus comprising an administering apparatus. The administering apparatus comprises a container (1) having a cavity and used for accommodating an agent, a catheter (2) in communication with the container (1) and used for introducing the agent in the container (1) into the nasal cavity, and a spray nozzle (4) arranged at an extremity of the catheter (2). The extremity of the catheter (2) can be extended into the olfactory area above a horizontal position corresponding to the middle nasal concha. The administering apparatus also comprises a pressure-sensitive film (3) that is arranged within the container (1), is used for separating the cavity of the container (1) into multiple discrete cavities (8 and 9), and ruptures under pressure. The other extremity of the catheter (2) is connected to one among the multiple cavities (8 and 9). The administering apparatus also comprises a soluble film (9) that is used for separating a lumen of the catheter (2) from the cavity (8) connected thereto and dissolves either partially or completely upon contact with the agent. The drug delivery apparatus allows highly efficient delivery of the agent to the olfactory area for direct absorption by the brain, thus providing therapeutic effects to the central nervous system.Linvention concerne un dispositif jetable dadministration par voie intranasale dun médicament dont la cible est le cerveau comprenant un applicateur, lequel applicateur comporte un conteneur (1) destiné au stockage dune formulation et une cavité interne, un cathéter (2) destiné à introduire dans la cavité nasale la formulation contenue dans le conteneur (1) auquel est relié le cathéter (2) et un atomiseur (4) placé sur une extrémité du cathéter (2), laquelle extrémité pénètre, à travers les voies nasales dun corps humain, la région de la cavité nasale au-dessus de la position horizontale correspondant au cornet nasal moyen. Lapplicateur comporte également un film se
