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1,3-DISUBSTITUTED-4-PHENYL-3,4,5,6-TETRAHYDRO-2H, 1H-[1,4] BIPYRIDINYL-2-ONES
专利权人:
ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS; INC
发明人:
CID-NUNEZ, JOSE MARIA,TRABANCO-SUAREZ, ANDRES, AVELINO,MACDONALD, GREGOR, JAMES,DUVEY, GUILLAUME, ALBERT, JACQUES,LUTJENS, ROBERT, JOHANNES,FINN, TERRY, PATRICK
申请号:
NZ58414508
公开号:
NZ584145A
申请日:
2008.09.12
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound having the formula (I) or a stereo chemically isomeric form thereof, wherein: R1 is C1-6alkyl or C1-3alkyl substituted with C3-7cycloalkyl, phenyl, or phenyl substituted with halo, trifluoromethyl or trifluoromethoxy R2 is halo, trifluoromethyl, C1-3alkyl or cyclopropyl R3 is hydrogen, fluoro, hydroxyl, hydroxyC1-3alkyl, hydroxyC1-3alkyloxy, fluoroC1-3alkyl, fluoroC1-3alkyloxy or cyano and Ar is unsubstituted phenyl or phenyl substituted with n radicals R4 wherein n is 1, 2 or 3 or a pharmaceutically acceptable salt or a solvate thereof.
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