IMIDAZO [1, 2 - B] PYRIDAZINE - BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND USES THEREOF

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专利权人:

LEXICON PHARMACEUTICALS; INC.

发明人:

BI, YINGZHI,CARSON, KENNETH GORDON,CIANCHETTA, GIOVANNI,GREEN, MICHAEL ALAN,KUMI, GODWIN,LIANG, ZHI,LIU, YING JADE,MAIN, ALAN,ZHANG, YULIAN,ZIPP, GLENN GREGORY

申请号：

SG11201405563V

公开号：

SG11201405563VA

申请日:

2013.03.05

申请国别(地区):

SG

年份:

2014

代理人:

摘要：

Imidazo[1,2-b]pyridazine-based compounds of the formula (I): are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.

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