PEREZ, MICHEL,LAMOTHE, MARIE,LE GRAND, BRUNO,LETIENNE, ROBERT
申请号：
HK09107160.0
公开号：
HK1127353B
申请日:
2009.08.05
申请国别(地区):
HK
年份:
2013
代理人:
摘要：
The present invention relates to compounds of general formula (I): wherein: R1 represents: halogen, CN or NO2； R2 represents: hydrogen or halogen； n represents: 1 or 2； R3 represents: phenyl substituted by one or more halogens or C1-C6 alkyls； or a cyclohexyl； as well as the therapeutically-acceptable salts or solvates thereof. These compounds are useful as protease-activated receptor-1 (PAR-1) antagonists, particularly in the treatment of thrombosis.
