Marie Lamothe;Michel PEREZ;Robert Letienne;Bruno Le Grand
发明人:
Michel PEREZ,Marie Lamothe,Bruno Le Grand,Robert Letienne
申请号：
US13476487
公开号：
US20120232097A1
申请日:
2012.05.21
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compounds of general formula (I):wherein:R1 represents: halogen, CN or NO2；R2 represents: hydrogen or halogen；n represents: 1 or 2；R3 represents: phenyl substituted by one or more halogens or C1-C6 alkyls； or a cyclohexyl；as well as the therapeutically-acceptable salts or solvates thereof.These compounds are useful as protease-activated receptor-1 (PAR-1) antagonists, particularly in the treatment of thrombosis.
