A rigid double-port tube with medicine dispensing nozzle for the big transfusion soft bag, which consists of a rigid double-port (1) and a medicine dispensing nozzle (2) through which the medicine is dispensed, through the rigid double-port (1) the medicine is infused into the soft bag and the medicine liquid is exported from the soft bag the rigid double-port (1) consists of a medicine infusing port (11), a medicine dispensing port (12) disposed parallel to the medicine infusing port (11), and the connecting base (13) connecting the medicine infusing port (11) and the medicine dispensing port (12), the medicine dispensing port (12) is connected with the medicine dispensing nozzle (2) hermetically a sealing rubber plug (22) used to medicine dispensing is disposed onto the medicine dispensing nozzle (2), the sealing rubber plug (22) can be pierced by the syringe pinhead and it contracts and closes automatically after the syringe pinhead being pulled out.