SOLVATE D'AMINE D'UN INHIBITEUR DE TRANSPORTEUSE LIE AU SODIUM-GLUCOSE, SON PROCEDE DE PREPARATION ET SON APPLICATION

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专利权人:

LTD.;YOUNGENE THERAPEUTICS CO.

发明人:

ZHANG, LEI,WANG, YUAN

申请号：

CA3016273

公开号：

CA3016273A1

申请日:

2017.03.27

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Disclosed are an amine solvate of a sodium-glucose linked transporter (SGLT) inhibitor, and a preparation method and application thereof. The SGLT inhibitor is (1S,2S,3S,4R,5S)-5-(3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-4-ethylbenzyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. Further provided is a crystalline compound of the amine solvate, a pharmaceutical composition comprising the amine solvate, and an application of the amine solvate in preparing an SGLT-inhibiting pharmaceutical product.

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