SOLVATE D'AMINE D'UN INHIBITEUR DE TRANSPORTEUSE LIÉ AU SODIUM-GLUCOSE, SON PROCÉDÉ DE PRÉPARATION ET SON APPLICATION

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专利权人:

YOUNGENE THERAPEUTICS CO.; LTD.

发明人:

ZHANG, Lei,WANG, Yuan

申请号：

EP17792395

公开号：

EP3453712A4

申请日:

2017.03.27

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Disclosed are an amine solvate of a sodium-glucose linked transporter (SGLT) inhibitor, and a preparation method and application thereof. The SGLT inhibitor is (1 S ,2 S ,3 S ,4 R ,5 S )-5-(3-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-4-ethylbenzyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol. Further provided is a crystalline compound of the amine solvate, a pharmaceutical composition comprising the amine solvate, and an application of the amine solvate in preparing an SGLT-inhibiting pharmaceutical product.

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