Amide-substituted heterocyclic compounds useful as modulators of il-12, il-23 and/or ifn alpha responses

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

Tokarski, John S.,Moslin, Ryan M.,Weinstein, David S.,Wrobleski, Stephen T.,Kumar, Amit,Batt, Douglas,Lin, Shuqun,Liu, Chunjian,Spergel, Steven,Zhang, Yanlei

申请号：

NZ70885913

公开号：

NZ708859A

申请日:

2013.11.07

申请国别(地区):

NZ

年份:

2018

代理人:

摘要：

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa, by acting on Tyk-2 to cause signal transduction inhibition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/