Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses

• 收藏
• 分享

专利权人:

Bristol-Myers Squibb Company

发明人:

Moslin, Ryan M.,Weinstein, David S.,Wrobleski, Stephen T.,Tokarski, John S.,Kumar, Amit,Batt, Douglas G.,Lin, Shuqun,Liu, Chunjian,Spergel, Steven H.,Zhang, Yanlei

申请号：

AU2013341186

公开号：

AU2013341186B2

申请日:

2013.11.07

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/