Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFN alpha responses

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

Moslin, Ryan M.,Weinstein, David S.,Wrobleski, Stephen T.,Tokarski, John S.,Kumar, Amit,Batt, Douglas G.,Lin, Shuqun,Liu, Chunjian,Spergel, Steven H.,Zhang, Yanlei

申请号：

AU2017201076

公开号：

AU2017201076A1

申请日:

2017.02.17

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017201076A120170309.pdf#####ABSTRACT Compounds having the following formula I: O R4 N R3 R1, 'j HR2 R5 5 R or a stereoisomer or pharmaceutically-acceptable salt thereof, where RI, R 2, R3 , R 4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNu, by acting on Tyk-2 to cause signal transduction inhibition. - 208 -

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