Moslin, Ryan M.,Weinstein, David S.,Wrobleski, Stephen T.,Tokarski, John S.,Kumar, Amit,Batt, Douglas G.,Lin, Shuqun,Liu, Chunjian,Spergel, Steven H.,Zhang, Yanlei
申请号：
AU2018267545
公开号：
AU2018267545A1
申请日:
2018.11.19
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018267545A120181213.pdf#####ABSTRACT This invention relates to compounds useful in the modulation of IL-12, IL-23 and/or IFNa by acting on Tyk-2 to cause signal transduction inhibition. Provided herein are amide-substituted heterocyclic compounds, compositions comprising such compounds, and methods of their use. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention that are useful for the treatment of conditions related to the modulation of IL-12, IL-23 and/or IFNa in a mammal. R4 R3 0 R 1W I ONY H 2I N N RI
