The invention discloses the use of cantaloupe and eggplant leaves and their extracts, which can be used to effectively prevent and / or improve alcoholic liver disease, in particular, the alcoholic liver disease is alcohol induced liver disease, such as alcoholic fatty liver, alcoholic hepatitis, abnormal liver lipid metabolism caused by alcohol.本發明係揭露一種將香瓜茄葉及其萃取物之用途,其係能夠用於有效地預防及/或改善酒精性肝臟疾病,具體來說,該酒精性肝臟疾病係為酒精誘發之肝臟病變,如酒精性脂肪肝、酒精性肝炎、酒精所引起之肝臟脂質代謝異常。