The present invention relates to a method of producing tablet candies having the effect of preventing alcoholic fatty liver by comprising an ethanol extract of Sedum sarmentosum. In the present invention, alcohol and Sedum sarmentosum tablet candies are administered to rats over 8 weeks, and the effect of the Sedum sarmentosum tablet candies as a functional health food was evaluated by changes in alcoholic fatty liver biomarkers. The alcohol administered group had a decrease in body weight, compared to the control group. Decrease in body weight was observed in the positive control group and the Sedum sarmentosum tablet candy treated group as well, however the decrease was significantly smaller, compared to the ethanol administered group. In the alcohol administered group, weight of liver tissues and fat concentration in liver tissues were increased, however when the Sedum sarmentosum tablet candies and alcohol were administered together, the expression of alcoholic fatty liver was significantly reduced. Vacuolation of liver cells was observed in periportal area in the ethanol administered group and the Sedum sarmentosum tablet candy administered group. Vacuolation of liver cells was observed in the control group as well, however the vacuolation was diffuse, and the vacuoles were typically small, compared to the alcohol administered group. Based on these characteristics, vacuolation observed in the control group was assumed to be glycogen deposit, not fatty degeneration. The positive control material was shown to prevent alcohol-induced fatty liver. Additionally, it was shown that development of alcohol-induced fatty liver can be inhibited by ingesting the Sedum sarmentosum tablet candies along with alcohol.COPYRIGHT KIPO 2017본 발명은 돌나물의 에탄올 추출물을 첨가하여 알코올성 지방간 발생을 예방하는 효능을 지닌 타정 캔디의 제조방법에 관한 것이다. 더 구체적으로 본 발명은 백서에 8주간 알코올과 돌나물 타정 캔디를 급여하여 알코올성 지방간의 바이오마커 변화를 통해 돌나물 타정 캔디의 건강기능성 식품으로서의 효능을 평가하고자 한다. 알코올 투여구는 대조구에 비하여 체중이 감소하였다. 양성대조구 및 돌나물 캔디 처리구에서도 체중 감소 현상은 관측되었으나 e
