The present invention relates to a use of Lactobacillus strain capable of reducing alcohol liver lesion and a composition for reducing alcohol liver lesion, comprising Lactobacillus strain with the function of reducing alcohol liver lesion, wherein the Lactobacillus strain is selected from the group consisting of Lactobacillus salivarius BCRC14759 or Lactobacillusjohnsonii BCRC17010.本發明係關於一種乳酸菌株用於降低酒精性肝損傷之用途,及一種降低酒精性肝損傷之組合物,其包含具有降低酒精性肝損傷功能之乳酸菌株,其中,該乳酸菌株為唾液乳酸桿菌(Lactobacillus salivarius) BCRC14759或約氏乳酸桿菌(Lactobacillus johnsonii)BCRC17010所組成的群組。