Roger Kingdon Craig;Richard Wilhelm Janssens;Marinus Johannes Van Haperen;Franklin Gerardus Grosveld
发明人:
Roger Kingdon Craig,Franklin Gerardus Grosveld,Richard Wilhelm Janssens,Marinus Johannes Van Haperen
申请号：
US13815676
公开号：
US09131669B2
申请日:
2013.03.14
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A transgenic non-human mammal containing a heterologous lambda light chain gene locus, and/or a heterologous kappa light chain gene locus, and/or a heterologous heavy chain gene locus, each of which can re-arrange so that immunoglobulin heavy and light chain genes are formed and expressed in B-cells following antigen challenge.
