Erasmus University Medical Center;Roger Kingdon Craig
发明人:
Roger Kingdon Craig,Franklin Gerardus Grosveld,Richard Wilhelm Janssens,Marinus Johannes Van Haperen
申请号：
US14806802
公开号：
US20160295842A1
申请日:
2015.07.23
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A transgenic non-human mammal containing a heterologous lambda light chain gene locus, and/or a heterologous kappa light chain gene locus, and/or a heterologous heavy chain gene locus, each of which can re-arrange so that immunoglobulin heavy and light chain genes are formed and expressed in B-cells following antigen challenge.
