To determine a time point at which the inside of an object during freeze-drying is completely dried, in a non-destructive manner.SOLUTION: A internal dry state determination method for a freeze-drying object is a method for determining an internal dry state of an object subjected to freeze-drying, and comprises: a detection step of making a resonance electromagnetic field, which is formed by using a microwave resonator, act on the object, and detecting at least one of the resonance frequency and resonance peak voltage of the resonance electromagnetic field and a determination step of determining a time point at which the inside of the object is completely dried on the basis of secular change of the detection value obtained in the detection step.SELECTED DRAWING: Figure 3【課題】凍結乾燥中の物品内部の乾燥完了時点を非破壊で判定可能にする。【解決手段】一実施形態に係る凍結乾燥物品の内部乾燥状態判定方法は、凍結乾燥中に凍結乾燥される物品の内部乾燥状態を判定する方法であって、前記物品にマイクロ波共振器を用いて形成されるマイクロ波の共振電磁場を作用させ、前記共振電磁場の共振周波数又は共振電圧の少なくとも一方を検出する検出ステップと、前記検出ステップで得た検出値の経時変化に基づいて前記物品の内部の乾燥完了時点を判定する判定ステップと、を備える。【選択図】図3