PROBLEM TO BE SOLVED: To provide a method for producing an adhesive patch obtainable of an adhesive patch excellent in properties of a self-adhesive layer by minimizing an influence on properties of the self-adhesive layer caused by lactic acid.SOLUTION: This method for producing adhesive patch includes processes of: (a) forming a self-adhesive layer containing a drug (excluding 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro cycloocta[b]pyridine and a physiologically acceptable acid addition salt thereof), an acrylic polymer, and an organic liquid component compatible with the acrylic polymer, and not containing lactic acid and (b) allowing the self-adhesive layer to contain lactic acid therein.COPYRIGHT: (C)2012,JPO&INPIT【課題】乳酸による粘着剤層の物性への影響を最小化し、粘着剤層の物性に優れる貼付製剤を得ることができる貼付製剤の製造方法の提供。【解決手段】(a):薬物(但し、2-(4-エチル-1-ピペラジニル)-4-(4-フルオロフェニル)-5,6,7,8,9,10-ヘキサヒドロキシクロオクタ[b]ピリジン及びその生理学的に許容される酸付加塩を除く)、アクリル系ポリマー及び該アクリル系ポリマーと相溶する有機液状成分を含有し、乳酸を含有しない粘着剤層を形成する工程と、(b):前記粘着剤層中に乳酸を含有させる工程とを有する、貼付製剤の製造方法。【選択図】なし
