通過CCR6阻斷CCL18信號作為纖維化疾病及癌症的治療選擇

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专利权人:

UNIVERSITTSKLINIKUM FREIBURG

发明人:

ZISSEL, GERNOT,MLLER-QUERNHEIM, JOACHIM,PRASSE, ANTJE

申请号：

HK12100260.9

公开号：

HK1159525B

申请日:

2012.01.10

申请国别(地区):

HK

年份:

2015

代理人:

摘要：

The present invention relates to an isolated polypeptide capable of binding to and inhibiting the activity of the chemokine receptor CCR6 and to a method for identifying further inhibitors of CCR6 receptor activity. The present invention also relates to a method for detecting an interstitial lung disease or a cancer in a subject by determining the level of CCR6 gene expression in a sample from said subject and further provides pharmaceutical compositions comprising inhibitors of CCR6 receptor activity and/or expression for the treatment of said diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/