The present invention relates to substituted thienopyrimidine compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.本發明係關於如本文所闡述及定義之通式(I)之經取代噻吩并嘧啶化合物、製備該等化合物之方法、可用於製備該等化合物之中間體化合物、包括該等化合物之醫藥組合物及組合及該等化合物用以製造醫藥組合物之用途,該醫藥組合物作為單獨藥劑或與其他活性成份組合用於治療或預防疾病、特定而言過度增殖性及/或血管生成病症。
