The present invention relates to substituted imidazopyridazine compounds of general formula I :in which R3, R5, and A are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.本發明係關於通式I之經取代咪唑并嗒化合物,其中R3、R5及A如申請專利範圍中所定義,製備該等化合物之方法,包含該等化合物之醫藥組合物及組合,以及以該等化合物作為唯一藥劑或與其他活性成分組合用於製造供治療或預防疾病(特定言之過度增生性及/或血管生成病症)之醫藥組合物上的用途。
