The present invention relates to substituted pyrrolopyrimidinylamino-benzothiazolone compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.本發明係關於如本文中描述及定義的通式I之經取代之吡咯并嘧啶胺基苯并噻唑酮化合物;製備該等化合物之方法;適用於製備該等化合物之中間化合物;包含該等化合物之醫藥組合物及組合;及該等化合物用於製造以單獨藥劑形式或與其他活性成分組合治療或預防疾病、尤其過度增生及/或血管生成病症之醫藥組合物之用途。