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Condensed ring pyridine compounds as subtype-selective modulators of sphingosine-1-phosphate-2 (S1P2) receptors
专利权人:
Inc.;Allergan
发明人:
Fang, Wenkui Ken,Wang, Liming,Corpuz, Evelyn G.,Chow, Ken,Im, Wha Bin
申请号:
AU2010300791
公开号:
AU2010300791A1
申请日:
2010.09.28
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases; systemic vascular barrier related diseases; allergies and other inflammatory diseases; cardiac diseases or conditions; fibrosis; pain and wounds.
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