FANG, WENKUI KEN,WANG, LIMING,CORPUZ, EVELYN G.,CHOW, KEN,IM, WHA BIN
申请号：
SG2012022794
公开号：
SG179727A1
申请日:
2010.09.28
申请国别(地区):
SG
年份:
2012
代理人:
摘要：
The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R3 are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases systemic vascular barrier related diseases allergies and other inflammatory diseases cardiac diseases or conditions fibrosis pain and wounds.
