FANG WENKUI KEN,WANG LIMING,CORPUZ EVELYN G,CHOW KEN,IM WHA BIN
申请号:
ZA201202366
公开号:
ZA201202366B
申请日:
2012.04.02
申请国别(地区):
ZA
年份:
2012
代理人:
摘要:
The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and/or antagonist biological activity, wherein these compounds selected from the group consisting of wherein A, B, C, D, X, Y, Z and R3 are defined in the specification. Said compounds are useful for treating a disease or condition of a mammal selected from the group consisting of ocular diseases; systemic vascular barrier related diseases; allergies and other inflammatory diseases; cardiac diseases or conditions; fibrosis; pain and wounds.