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SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDES AND ANALOGS THEREOF, AND METHODS USING SAME
专利权人:
ARBUTUS BIOPHARMA CORPORATION
发明人:
COLE, Andrew,DORSEY, Bruce,KAKARLA, Ramesh,KULTGEN, Steven,QUINTERO, Jorge
申请号:
SG11201908569Q
公开号:
SG11201908569QA
申请日:
2018.03.20
申请国别(地区):
SG
年份:
2019
代理人:
摘要:
Filing Language: (26) Publication Language: (30) Priority Data: 62/474,263 62/588,711 20 March 2018 (20.03.2018) English English 21 March 2017 (21.03.2017) US 20 November 2017 (20.11.2017) US (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 27 September 2018 (27.09.2018) WIPO I PCT omit VIII °nolo VIII 1111101 ois (10) International Publication Number WO 2018/172852 Al (51) International Patent Classification: C07C 275/26 (2006.01) CO7D 235/02 (2006.01) A61K 31/17 (2006.01) CO7D 239/42 (2006.01) A61K 31/27 (2006.01) CO7D 275/06 (2006.01) A61K 31/33 (2006.01) CO7D 307/82 (2006.01) A61P 31/20 (2006.01) CO7D 333/54 (2006.01) CO7C 271/24 (2006.01) CO7D 401/06 (2006.01) CO7D 213/30 (2006.01) CO7D 401/12 (2006.01) CO7D 213/40 (2006.01) CO7D 405/12 (2006.01) CO7D 221/04 (2006.01) CO7D 409/12 (2006.01) (21) International Application Number: PCT/IB2018/000387 (22) International Filing Date: UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (71) Applicant: ARBUTUS BIOPHARMA CORPO- RATION [CA/CA]; 100-8900 Glenlyon Parkway, Burna- by, BC V5J5J8 (CA). = (72) Inventors: COLE, Andrew, G.; 65 Rocky Brook Road, Cranbury, NJ 08512 (US). DORSEY, Bruce, D.; 1213 Meetinghouse Road, Ambler, PA 19002 (US). KAKAR- LA, Ramesh; 5008 Grundy Way, Doylestown, PA 18902 (US). KULTGEN, Steven; 261 Evergreen Avenue, Apt. A, Hamilton, NJ 08619 (US). QUINTERO, Jorge; 68
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