Breast cancer, lung cancer, stomach cancer, ovarian cancer, hepatocellular cancer, colon cancer, pancreatic cancer, esophageal cancer, head and neck cancer, renal cancer, renal cell carcinoma, prostate cancer, liver cancer, melanoma, sarcoma, the present invention is, in particular myeloma, thyroid cancer neuroblastoma, placental choriocarcinoma, uterine cancer, and therapies for prevention and / or treating a disease associated, including tumor-related diseases such as metastatic forms thereof, to a cell expressing GT468 is to provide a useful antibody as medicine. In one embodiment, the cancer disease is metastatic cancer of the lung.本発明は、乳癌、肺癌、胃癌、卵巣癌、肝細胞癌、結腸癌、膵癌、食道癌、頭頸部癌、腎癌、特に腎細胞癌、前立腺癌、肝癌、黒色腫、肉腫、骨髄腫、神経芽細胞腫、胎盤性絨毛癌、子宮頸癌および甲状腺癌、ならびにそれらの転移形態などの腫瘍関連疾患を含む、GT468を発現する細胞に関連する疾患を治療するおよび/または予防するための治療薬として有用な抗体を提供する。1つの実施形態では、癌疾患は肺の転移性癌である。