Novel antifungal 5,6-dihydro-4-[(difluoroethyl)phenyl]-4H-pyrrolo[1,2-a][1,4]-benzodiazepine and 4-(difluoroethyl)phenyl-6H-pyrrolo[1,2-a][1,4]benzodiazepine derivatives

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

MAES LOUISE JULES ROGER MARIE,WIT KELLY DE,MEERPOEL LIEVEN

申请号：

AP2012006502

公开号：

AP3285A

申请日:

2011.06.01

申请国别(地区):

AP

年份:

2015

代理人:

摘要：

The present invention concerns novel compounds of Formula (I): wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/