Novel antifungal 5,6-dihydro-4-[(difluoroethyl) phenyl] -4H-pyrrolo [1,2-a] [1,4] benzodiazepine and 4- (difluoroethyl) phenyl-6H-pyrrolo [1, 2-a] [1,4] benzodiazepine derivatives

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专利权人:

ヤンセン;ヤンセン ファーマシューティカ エヌ.ベー.;ファーマシューティカ;エヌ．ベー．

发明人:

リーベン・メールポール,ルイ・ジユール・ロジエ・マリー・マース,ケリー・ドウ・ウイツト

申请号：

JP2016004295

公开号：

JP6208263B2

申请日:

2016.01.13

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention concerns novel compounds of Formula (I): wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.

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中国工程科技知识中心

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http://www.ckcest.cn/home/