NOUVEAUX DÉRIVÉS DE 3'-DÉSOXYADÉNOSINE PRÉSENTANT UN FRAGMENT ESTER DE PHOSPHORAMIDATE ET D'ACIDE AMINÉ 2' ET/OU 5' COMME COMPOSÉS ANTICANCÉREUX

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专利权人:

Nucana PLC

发明人:

申请号：

EP19181028.2

公开号：

EP3683225A1

申请日:

2015.11.27

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to chemical compounds, the compounds for us in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours in homo sapiens. The compounds are derivatives of cordycepin (3'-deoxyadenosine) having a 2' and/or 5'-amino-acid ester phosphoramidate moiety.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/