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NOVOS DERIVADOS DE 3¿-DESOXIADENOSINA COM FOSFORAMIDATOS DE ÉSTERES DE AMINOÁCIDOS EM 2¿ E/OU 5¿ COMO COMPOSTOS ANTICANCERÍGENOS
专利权人:
NUCANA PLC
发明人:
HUGH GRIFFITH,CHRISTOPHER MCGUIGAN,VALENTINA FERRARI,MICHAELA SERPI,CARMEN JIMENEZ ANTUNEZ
申请号:
PT15804216
公开号:
PT3224268T
申请日:
2015.11.27
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
Disclosed are chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours in homo sapiens. The compounds are derivatives of cordycepin (3′-deoxyadenosine) having a 2′ and/or 5′-amino-acid ester phosphoramidate moiety.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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