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Nowe pochodne 3'-deoksyadenozyny amidofosforanów estrów aminokwasów 2' i/lub 5' jako związki przeciwnowotworowe
专利权人:
NuCana plc
发明人:
GRIFFITH, HUGH,MCGUIGAN, CHRISTOPHER,FERRARI, VALENTINA,SERPI, MICHAELA,JIMENEZ ANTUNEZ, CARMEN
申请号:
PL15804216
公开号:
PL3224268T3
申请日:
2015.11.27
申请国别(地区):
PL
年份:
2019
代理人:
摘要:
Disclosed are chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours in Homo sapiens. The compounds are derivatives of cordycepin (3′-deoxyadenosine) having a 2′ and/or 5′-amino-acid ester phosphoramidate moiety.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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