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New 2' and/or 5' amino-acid ester phosphoramidate 3'-deoxy adenosine derivatives as anti-cancer compounds
专利权人:
NuCana plc
发明人:
Griffith, Hugh,McGuigan, Christopher,Ferrari, Valentina,Serpi, Michaela,Jimenez Antunez, Carmen
申请号:
AU2019232929
公开号:
AU2019232929A1
申请日:
2019.09.20
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019232929A120191010.pdf#####C: Interwo n NRPortbl DCCSXD 19329517_l.docx-l9/09/2019 ABSTRACT The present invention relates to chemical compounds, the compounds for use in a method of treatment, particularly in a method of prophylaxis or treatment for cancer, a process for preparation of the compounds and pharmaceutical compositions comprising the compounds. The compounds may, in particular, be useful in the treatment of leukaemia, lymphoma and/or solid tumours inhomo sapiens. The compounds are derivatives of cordycepin (3'-deoxyadenosine) having a 2' and/or 5'-amino-acid ester phosphoramidate moiety.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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