噻托銨鹽、包含噻托銨鹽的藥物製劑及其用途

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

BANHOLZER, ROLF,PFRENGLE, WALDEMAR,SIEGER, PETER

申请号：

HK09108607.9

公开号：

HK1129111B

申请日:

2007.05.25

申请国别(地区):

HK

年份:

2014

代理人:

摘要：

Preparation of new tiotropilium salts (1) by subjecting a different tiotropilium salt (2) to anion exchange with an ion source in a solvent. Preparation of new tiotropilium salts of formula (1) by subjecting a different tiotropilium salt of formula (2) to anion exchange with an ion source (Kat-X) in a solvent. [Image] X : anion； Y : anion, different from X, i.e. halo, 1-10C alkyl-sulfonate or -sulfate, or 6-10C arylsulfonate； Kat : cation. An independent claim is also included for new compounds (1) and (2), except where Y/X = bromo, optionally as solvates or hydrates. ACTIVITY : Antiasthmatic. No details of tests for antiasthmatic activity are given. MECHANISM OF ACTION : Anticholinergic.

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