Sara Iva Siebel,Edward Derrick Pascua,Chia-Yang Lin,Javier Fernando Chaparro Riggers
申请号：
US14367483
公开号：
US09249224B2
申请日:
2012.12.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides antagonizing antibodies that bind to growth hormone receptor (GHR). The invention further relates to therapeutic methods for use of these antibodies to reduce IGF-1 levels and/or for the treatment and/or prevention of diseases associated with excessive IGF-1, including treatment of acromegaly, gigantism, cancer, diabetic nephropathy, arthritis, and lung inflammation.
