SIEBEL SARA IVA,PASCUA EDWARD DERRICK,LIN CHIA YANG,CHAPARRO RIGGERS JAVIER FERNANDO
申请号:
IN4652CHN2014
公开号:
IN4652CHN2014A
申请日:
2014.06.19
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention provides antagonizing antibodies that bind to growth hormone receptor (GHR). The invention further relates to therapeutic methods for use of these antibodies to reduce IGF 1 levels and/or for the treatment and/or prevention of diseases associated with excessive IGF 1 including treatment of acromegaly gigantism cancer diabetic nephropathy arthritis and lung inflammation.