Siebel, Sara Iva,Pascua, Edward Derrick,Lin, Chia-Yang,Chaparro Riggers, Javier Fernando
申请号：
AU2012356206
公开号：
AU2012356206A1
申请日:
2012.12.10
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention provides antagonizing antibodies that bind to growth hormone receptor (GHR). The invention further relates to therapeutic methods for use of these antibodies to reduce IGF-1 levels and/or for the treatment and/or prevention of diseases associated with excessive IGF-1, including treatment of acromegaly, gigantism, cancer, diabetic nephropathy, arthritis, and lung inflammation.
