JEONG, TAE SOOK,정태숙,BAEK, NAM IN,백남인,LEE, KYUNG TAE,이경태,CHOI, MYUNG SOOK,최명숙,CHUNG, HAE GON,정해곤,KANG, EUN KYUNG,강은경
申请号：
KR1020100131319
公开号：
KR1020120069964A
申请日:
2010.12.21
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: An anti-obesity composition containing 1-methoxy indole-3-acetonitrile or 4-methoxy indole-3-acetonitrile is provided to ensure excellent and safe anti-obesity function.CONSTITUTION: An anti-obesity composition contains 1-methoxy indole-3-acetonitrile or 4-methoxy indole-3-acetonitrile as an active ingredient. The active ingredient is isolated from Brassica rapa. A method for preparing 1-methoxy indole-3-acetonitrile comprises: a step of extracting Brassica rapa. with methanol a step of extracting the methanol extract with ethyl acetate/H_2O and isolating an H_2O layer with n-BuOH/H_2O a step of decompressing each layer to obtain ethyl acetate fraction, n-butanol fraction, and water fraction a step of performing silicagel column chromatography of the ethyl acetate fraction and a step of purifying 7th fraction(BE7 fraction) with octadesyl silicagel.COPYRIGHT KIPO 2012본 발명은 1-메톡시인돌-3-아세토니트릴 또는 4-메톡시인돌-3-아세토니트릴 중에서 선택된 하나 이상을 유효성분으로 함유하는 항비만용 조성물을 제공한다. 본 발명의 조성물은 우수하고, 안전한 항비만 효과를 가진다는 장점을 갖는다.
