JEONG, TAE SOOK,정태숙,BAEK, NAM IN,백남인,LEE, KYUNG TAE,이경태,CHOI, MYUNG SOOK,최명숙,CHUNG, HAE GON,정해곤,KANG, EUN KYUNG,강은경
申请号：
KR1020100131321
公开号：
KR1020120069965A
申请日:
2010.12.21
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: An anti-obesity composition containing zingerone-4-O-beta-glucopyranoside is provided to ensure safe anti-obesity effect.CONSTITUTION: An anti-obesity composition contains zingerone-4-O-beta-glucopyranoside as an active ingredient. The active ingredient is isolated from Brassica rapa. A method for preparing zingerone-4-beta-glucopyranoside comprises: a step of extracting Brassica rapa. with methanol a step of extracting the methanol extract with ethanolacetate/water and extracting a water layer with n-butanol/water a step of decompressing each layer to prepare an ethanol acetate, n-butanol, and water fractions a step of performing silicagel column chromatography of the n-butanol fraction to prepare 16 fractions(BRB-1 to BRB-16) a step of performing silica gel column chromatography of 6th fraction among 16 fractions to obtain 12 small fractions(BRB-6-1 to BRB-6-12) a step of performing silicagel column chromatography of 10th small fraction to obtain 7 small fractions(BRB-6-10-1 to BRB-6-10-7) and a step of purifying by octacetyl silicagel column chromatography. The composition is a food or pharmaceutical composition.COPYRIGHT KIPO 2012본 발명은 진거론-4-O-베타-글루코피라노사이드(zingerone-4-O-β-glucopyranoside)를 유효성분으로 함유하는 항비만용 조성물을 제공한다. 본 발명의 조성물은 우수하고, 안전한 항비만 효과를 가진다는 장점을 갖는다.
