Riley, James L.,Paulos, Chrystal,June, Carl H.,Levine, Bruce
申请号:
AU2014224141
公开号:
AU2014224141A1
申请日:
2014.09.15
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014224141A120141002.pdf#####ABSTRACT The invention includes compositions and methods for generating and expanding therapeutic Thl7 cells. The invention includes contacting T cells with a composition comprising a first agent that is capable of providing a primary activation 5 signal to T cells and a second agent that is capable of activating ICOS on T cells in the presence of Th- 17 polarizing agents.