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Method for Generating Human Multipotent Mammary Stem Cells From Normal Primary Breast Luminal Cells
专利权人:
发明人:
Abdelilah ABOUSSEKHRA,Huda H. AL-KHLAF,Hazem GHEBEH
申请号:
US15461043
公开号:
US20180265841A1
申请日:
2017.03.16
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to methods for generating multipotent mammary stem cells from isolated and cultured human breast luminal cells. The method comprises the steps: 1. isolating and growing normal differentiated cells in vitro 2. treating the differentiated cells with either a conditioned medium from active fibroblasts or cytokine. The invention also relates to multipotent mammary stem cells, cultures of the multipotent stern cells, differentiated cells, tissues, organs derived from the culture multipotent stem cells isolated by the methods disclosed and therapeutic and other uses for those cells thereof.
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