BI, YINGZHI,毕映枝,畢映枝,GARDYAN, MICHAEL WALTER,盖尔德彦麦可华特,蓋爾德彥麥可華特,GREEN, MICHAEL ALAN,葛林麦可亚伦,葛林麥可亞倫,KUMI, GODWIN,古米葛德温,古米葛德溫,ZHANG, YULIAN,张玉莲,張玉蓮
申请号：
TW103130825
公开号：
TW201542552A
申请日:
2014.09.05
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
Imidazo[1,2-b]pyridazine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.揭示了具有如下化學式的咪唑[1,2-b]噠嗪基化合物:其中R1、R2及R3如本文所定義。亦揭示了包括該等化合物的組成物,以及將其用於治療、管理及/或預防由適配器關聯激酶1活性介導的疾病及病症的方法。
