Disclosed are compounds of Formula 1, and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula 1, to pharmaceutical compositions which contain them, and to their use for treating immunological disorders, cardiovascular disease, cancer, and other diseases, disorders or conditions associated with PI3Kδ.本文揭露式1化合物，及其醫藥學上可接受之鹽，其中R1、R2、R3、R4、R5、R6、R7、R8、R9及R10係在說明書中定義。本揭露內容亦係關於用於製備式1化合物之材料及方法；含有該等式1化合物之醫藥組合物；以及其用於治療免疫病症、心血管疾病、癌症及與PI3Kδ相關之其他疾病、病症或病狀之用途。
