The present invention relates to a method for synthesizing an acylglycinate salt, and a human body detergent composition using the same and, more particularly, to a method for synthesizing an acylglycinate salt having an improved reaction yield and product purity by using a small amount of a solvent which is safe on a human body , and a human body detergent composition using the same. The method for synthesizing an acylglycinate salt of the present invention can remarkably improve the reaction yield and the purity of the product while using a small amount of a dipropylene glycol solvent which is safe on a human body. In addition, the human body cleaning composition containing acylglycinate, obtained by the method for synthesizing an acylglycinate salt of the present invention, has low cytotoxicity and allergenicity and is hypoallergenic.本發明涉及醯基甘氨酸酯鹽的合成方法、以及使用該方法的人體清潔用組合物,更具體而言,涉及一種以少量使用對人體安全的溶劑,從而提高了反應收率和生成物純度的醯基甘氨酸酯鹽的合成方法、以及使用該合成方法的人體清潔用組合物。本發明的醯基甘氨酸酯鹽的合成方法,在少量使用對人體安全的二丙二醇溶劑得情況下,能夠顯著提高反應收率和生成物的純度。另外,包含由本發明的醯基甘氨酸酯鹽的合成方法獲得的醯基甘氨酸酯的人體清潔用組合物,其細胞毒性和過敏誘導性低,且對皮膚的刺激性低。
