AMETAMEY, SIMON MENSAH,MOSER, RUDOLF,ROSS, TOBIAS LUDWIG,LAM, PHOEBE,GROEHN, VIOLA
申请号:
CA2670363
公开号:
CA2670363C
申请日:
2008.04.11
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention is directed towards a method ofsynthesis of 18F-folate radiopharmaceuticals, whereinfluorine-18 is attached to a pteroate (or folate) orderivative thereof, through direct radiolabeling with 18 [F]fluoride, as well as 18F-folate radiopharmaceuticals obtainedby such method of synthesis and their use in diagnosis andmonitoring of cancer therapy and therapy of inflammatory andautoimmune diseases.