The present invention relates to an orodispersible tablet having a hardness ranging from 30 to 80 N, and preferably from 40 to 75 N, comprising an active ingredient in the form of microcrystals or coated microgranules and a mixture of excipients chosen from the group comprising a diluent, a disintegrant, a sweetener, a binder, a flow agent, a humectant, a wetting agent, a lubricant, a flavoring agent, a colorant, and mixtures thereof, said mixture of excipients being in the form of grains characterized in that said tablet is obtained by a compression molding process comprising the following steps: - preparation by wetting of grain of excipients having a residual moisture ranging from 0.5% to 7%, preferably from 1 to 5%, and more preferably from 2 to 4%, - preparation of microcrystals or microgranules coated with active ingredient, - mixture of microcrystals or micron coated granules of active ingredient and grains of wet excipients prepared above, optionally, adding to the wet mixture for compression prepared above of excipients selected from the group consisting of a flow agent, a lubricant, a flavor, a sweetener and their mixtures； compression of the compression mixture prepared above to obtain a tablet； optionally drying of the tablet thus obtained.La présente invention a pour objet un comprimé orodispersible présentant une dureté allant de 30 à 80 N, et de préférence de 40 à 75 N, comprenant un principe actif sous forme de microcristaux ou de microgranules enrobés et un mélange d'excipients choisis dans le groupe comprenant un diluant, un désintégrant, un édulcorant, un liant, un agent d'écoulement, un humectant, un agent mouillant, un lubrifiant, un agent aromatisant, un colorant et leurs mélanges, ledit mélange d'excipients se présentant sous forme de grains, caractérisé en ce que ledit comprimé est obtenu par un procédé de compression moulage (« compression molding ») comprenant les étapes suivantes : - préparation par humidification de grains d'excipients pr
